Background and Objectives: Depersonalization is a prevalent symptom in mental disorder, brain-organic disease and substance and drug abuse. It is defined as a recurrent change in self perception. The aim of this study is to explore depersonalization in patients with temporal lobe epilepsy, panic disorder and non-patient control group.Methods and Materials: Here we studied the depersonalization level by Cambridge personalization scale in a group of patients with temporal lobe epilepsy and panic disorders. The same study was done in a normal control group.Results: Patients with temporal lobe epilepsy had a high score of depersonalization level (%35.87), followed by panic disorder patients (%31.53) and normal controls (%32.61). Conclusion: Depersonalization is a common phenomenon in temporal lobe epilepsy and panic disorder.

Background and Objectives panic disorder is one of the most common anxiety disorders that causes many problems for people and the community. This study aims to determine the severity of panic disorder based on cognitive avoidance, distress tolerance and cognitive flexibility in patients with panic disorder. Methods This is a correlational study with a predictive design conducted on 130 patients with panic disorder in Isfahan, Iran, who were selected by a sequential sampling method. In order to measure the study variables, the panic disorder Severity Scale, the Cognitive Avoidance Questionnaire, the Distress Tolerance Scale, and the Cognitive Flexibility Inventory were used. In order to analyze the collected data, we used Pearson correlation test and stepwise regression analysis in SPSS v. 23 software. Results The results showed that the severity of panic disorder was directly and significantly related to cognitive avoidance (P<0. 01) and significantly and indirectly related to distress tolerance (P<0. 01). The severity of panic disorder was indirectly related to cognitive flexibility, but it was not significant (P> 0. 05), although due to the direct and significant correlation between cognitive flexibility and cognitive avoidance (P<0. 01), a part of the relationship between panic disorder severity and cognitive flexibility was expected after mediation by cognitive avoidance. Conclusion Cognitive avoidance, distress tolerance, and cognitive flexibility have the ability to predict the severity of panic disorder.

Objectives: The present study was conducted to investigate the personality traits which may have a negative impact on patients' performance, health, and occurrence of panic disorder as well as its process and prognosis. Method: 51 subjects diagnosed with panic disorder were compared with 51 normal subjects through NEO Personality Inventory- Revised (NEO PI-R). Findings: The findings indicated that subjects suffering from panic disorder were more susceptible to experiences of anxiety, depression, aggression, guilt-feeling, and stress. They were less extraverted, but as capable of controlling their impulses as normal subjects; they prefer to have a stable life, and are not interested in experiencing adventures. Results: The study demonstrated that the personality traits of the subjects diagnosed with panic disorder more likely correlates with those of the Cluster C of personality disorders.